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Differential Mobility-Mass Spectrometry Double Spike Isotope Dilution Study of Release of β-Methylaminoalanine and Proteinogenic Amino Acids during Biological Sample Hydrolysis

The non-protein amino acid β-methylamino-L-alanine (BMAA) has been linked to neurodegenerative disease and reported throughout the environment. Proposed mechanisms of bioaccumulation, trophic transfer and chronic toxicity of BMAA rely on the hypothesis of protein misincorporation. Poorly selective m...

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Detalles Bibliográficos
Autores principales: Beach, Daniel G., Kerrin, Elliott S., Giddings, Sabrina D., Quilliam, Michael A., McCarron, Pearse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758758/
https://www.ncbi.nlm.nih.gov/pubmed/29311581
http://dx.doi.org/10.1038/s41598-017-18392-w