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A specific form of prefibrillar aggregates that functions as a precursor of amyloid nucleation

Non-fibrillar protein aggregates that appear in the earlier stages of amyloid fibril formation are sometimes considered to play a key role in amyloid nucleation; however, the structural features of these aggregates currently remain unclear. We herein identified a characteristic pathway of fibril for...

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Detalles Bibliográficos
Autores principales: Yamamoto, Naoki, Tsuhara, Shoko, Tamura, Atsuo, Chatani, Eri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758805/
https://www.ncbi.nlm.nih.gov/pubmed/29311640
http://dx.doi.org/10.1038/s41598-017-18390-y