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High content image analysis reveals function of miR-124 upstream of Vimentin in regulating motor neuron mitochondria

microRNAs (miRNAs) are critical for neuronal function and their dysregulation is repeatedly observed in neurodegenerative diseases. Here, we implemented high content image analysis for investigating the impact of several miRNAs in mouse primary motor neurons. This survey directed our attention to th...

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Detalles Bibliográficos
Autores principales: Yardeni, Tal, Fine, Raquel, Joshi, Yuvraj, Gradus-Pery, Tal, Kozer, Noga, Reichenstein, Irit, Yanowski, Eran, Nevo, Shir, Weiss-Tishler, Hila, Eisenberg-Bord, Michal, Shalit, Tal, Plotnikov, Alexander, Barr, Haim M., Perlson, Eran, Hornstein, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758812/
https://www.ncbi.nlm.nih.gov/pubmed/29311649
http://dx.doi.org/10.1038/s41598-017-17878-x