A WNT protein therapeutic improves the bone-forming capacity of autografts from aged animals

Autografts tend to be unreliable in older patients. Some of these age-related skeletal changes appear to be attributable to a decline in endogenous WNT signaling. We used a functional in vivo transplantation assay to demonstrate that the bone-forming capacity of an autograft can be traced back to a...

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Detalles Bibliográficos
Autores principales: Chen, Tao, Li, Jingtao, Córdova, Luis A., Liu, Bo, Mouraret, Sylvain, Sun, Qiang, Salmon, Benjamin, Helms, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758817/
https://www.ncbi.nlm.nih.gov/pubmed/29311710
http://dx.doi.org/10.1038/s41598-017-18375-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758817/
https://www.ncbi.nlm.nih.gov/pubmed/29311710
http://dx.doi.org/10.1038/s41598-017-18375-x

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