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Controllable deuteration of halogenated compounds by photocatalytic D(2)O splitting

Deuterium labeling is of great value in organic synthesis and the pharmaceutical industry. However, the state-of-the-art C–H/C–D exchange using noble metal catalysts or strong bases/acids suffers from poor functional group tolerances, poor selectivity and lack of scope for generating molecular compl...

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Detalles Bibliográficos
Autores principales: Liu, Cuibo, Chen, Zhongxin, Su, Chenliang, Zhao, Xiaoxu, Gao, Qiang, Ning, Guo-Hong, Zhu, Hai, Tang, Wei, Leng, Kai, Fu, Wei, Tian, Bingbing, Peng, Xinwen, Li, Jing, Xu, Qing-Hua, Zhou, Wu, Loh, Kian Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758826/
https://www.ncbi.nlm.nih.gov/pubmed/29311606
http://dx.doi.org/10.1038/s41467-017-02551-8