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C/EBPβ mediates RNA polymerase III-driven transcription of oncomiR-138 in malignant gliomas

MicroRNA-138 (miR-138) is a pro-survival oncomiR for glioma stem cells. In malignant gliomas, dysregulated expression of microRNAs, such as miR-138, promotes Tumour initiation and progression. Here, we identify the ancillary role of the CCAAT/enhancer binding protein β (C/EBPβ) as a transcriptional...

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Detalles Bibliográficos
Autores principales: Di Pascale, Federica, Nama, Srikanth, Muhuri, Manish, Quah, Shan, Ismail, Hisyam M, Chan, Xin Hui Derryn, Sundaram, Gopinath M, Ramalingam, Rajkumar, Burke, Brian, Sampath, Prabha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758869/
https://www.ncbi.nlm.nih.gov/pubmed/29136251
http://dx.doi.org/10.1093/nar/gkx1105