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The intrinsically disordered N-terminal arm of the brome mosaic virus coat protein specifically recognizes the RNA motif that directs the initiation of viral RNA replication

In the brome mosaic virus (BMV) virion, the coat protein (CP) selectively contacts the RNA motifs that regulate translation and RNA replication (Hoover et al., 2016. J. Virol. 90, 7748). We hypothesize that the unstructured N-terminal arm (NTA) of the BMV CP can specifically recognize RNA motifs. Us...

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Detalles Bibliográficos
Autores principales: Jacobs, Alexander, Hoover, Haley, Smith, Edward, Clemmer, David E, Kim, Chul-Hyun, Kao, C Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758871/
https://www.ncbi.nlm.nih.gov/pubmed/29140480
http://dx.doi.org/10.1093/nar/gkx1087