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Nanoscale dynamics of centromere nucleosomes and the critical roles of CENP-A
In the absence of a functioning centromere, chromosome segregation becomes aberrant, leading to an increased rate of aneuploidy. The highly specific recognition of centromeres by kinetochores suggests that specific structural characteristics define this region, however, the structural details and me...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758880/ https://www.ncbi.nlm.nih.gov/pubmed/29040671 http://dx.doi.org/10.1093/nar/gkx933 |