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Nanoscale dynamics of centromere nucleosomes and the critical roles of CENP-A

In the absence of a functioning centromere, chromosome segregation becomes aberrant, leading to an increased rate of aneuploidy. The highly specific recognition of centromeres by kinetochores suggests that specific structural characteristics define this region, however, the structural details and me...

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Detalles Bibliográficos
Autores principales: Stumme-Diers, Micah P, Banerjee, Siddhartha, Hashemi, Mohtadin, Sun, Zhiqiang, Lyubchenko, Yuri L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758880/
https://www.ncbi.nlm.nih.gov/pubmed/29040671
http://dx.doi.org/10.1093/nar/gkx933