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Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria
Mycobacterium tuberculosis (Mtb) encodes two CRP/FNR family transcription factors (TF) that contribute to virulence, Cmr (Rv1675c) and CRP(Mt) (Rv3676). Prior studies identified distinct chromosomal binding profiles for each TF despite their recognizing overlapping DNA motifs. The present study show...
Autores principales: | Ranganathan, Sridevi, Cheung, Jonah, Cassidy, Michael, Ginter, Christopher, Pata, Janice D, McDonough, Kathleen A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758884/ https://www.ncbi.nlm.nih.gov/pubmed/29165665 http://dx.doi.org/10.1093/nar/gkx1148 |
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