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Crystal structure of an anti-CRISPR protein, AcrIIA1

Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins provide bacteria with RNA-based adaptive immunity against phage infection. To counteract this defense mechanism, phages evolved anti-CRISPR (Acr) proteins that inactivate the CRISPR-Cas systems....

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Detalles Bibliográficos
Autores principales: Ka, Donghyun, An, So Young, Suh, Jeong-Yong, Bae, Euiyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758886/
https://www.ncbi.nlm.nih.gov/pubmed/29182776
http://dx.doi.org/10.1093/nar/gkx1181