Structure of mycobacterial 3′-to-5′ RNA:DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases

Mycobacterial Lhr is a DNA damage-inducible superfamily 2 helicase that uses adenosine triphosphate (ATP) hydrolysis to drive unidirectional 3′-to-5′ translocation along single-stranded DNA (ssDNA) and to unwind RNA:DNA duplexes en route. ATPase, translocase and helicase activities are encompassed w...

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Detalles Bibliográficos
Autores principales: Ejaz, Anam, Ordonez, Heather, Jacewicz, Agata, Ferrao, Ryan, Shuman, Stewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758891/
https://www.ncbi.nlm.nih.gov/pubmed/29165676
http://dx.doi.org/10.1093/nar/gkx1163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758891/
https://www.ncbi.nlm.nih.gov/pubmed/29165676
http://dx.doi.org/10.1093/nar/gkx1163

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