DNA polymerase beta participates in DNA End-joining

DNA double strand breaks (DSBs) are one of the most deleterious lesions and if left unrepaired, they lead to cell death, genomic instability and carcinogenesis. Cells combat DSBs by two pathways: homologous recombination (HR) and non-homologous end-joining (NHEJ), wherein the two DNA ends are re-joi...

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Detalles Bibliográficos
Autores principales: Ray, Sreerupa, Breuer, Gregory, DeVeaux, Michelle, Zelterman, Daniel, Bindra, Ranjit, Sweasy, Joann B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758893/
https://www.ncbi.nlm.nih.gov/pubmed/29161447
http://dx.doi.org/10.1093/nar/gkx1147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758893/
https://www.ncbi.nlm.nih.gov/pubmed/29161447
http://dx.doi.org/10.1093/nar/gkx1147

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