Mechanism of formation of a toroid around DNA by the mismatch sensor protein

The DNA mismatch repair (MMR) pathway removes errors that appear during genome replication. MutS is the primary mismatch sensor and forms an asymmetric dimer that encircles DNA to bend it to scan for mismatches. The mechanism utilized to load DNA into the central tunnel was unknown and the origin of...

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Detalles Bibliográficos
Autores principales: Nirwal, Shivlee, Kulkarni, Dhananjaya S, Sharma, Amit, Rao, Desirazu N, Nair, Deepak T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758902/
https://www.ncbi.nlm.nih.gov/pubmed/29182773
http://dx.doi.org/10.1093/nar/gkx1149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758902/
https://www.ncbi.nlm.nih.gov/pubmed/29182773
http://dx.doi.org/10.1093/nar/gkx1149

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