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Inhibition of DNA replication by an anti-PCNA aptamer/PCNA complex

Proliferating cell nuclear antigen (PCNA) is a multifunctional protein present in the nuclei of eukaryotic cells that plays an important role as a component of the DNA replication machinery, as well as DNA repair systems. PCNA was recently proposed as a potential non-oncogenic target for anti-cancer...

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Detalles Bibliográficos
Autores principales: Kowalska, Ewa, Bartnicki, Filip, Fujisawa, Ryo, Bonarek, Piotr, Hermanowicz, Paweł, Tsurimoto, Toshiki, Muszyńska, Klaudia, Strzalka, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758903/
https://www.ncbi.nlm.nih.gov/pubmed/29186524
http://dx.doi.org/10.1093/nar/gkx1184