The human papillomavirus DNA helicase E1 binds, stimulates, and confers processivity to cellular DNA polymerase epsilon

The papillomavirus (PV) helicase protein E1 recruits components of the cellular DNA replication machinery to the PV replication fork, such as Replication Protein A (RPA), DNA polymerase α-primase (pol α) and topoisomerase I (topo I). Here we show that E1 binds to DNA polymerase ϵ (pol ϵ) and dramati...

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Detalles Bibliográficos
Autores principales: Chojnacki, Michaelle, Melendy, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758917/
https://www.ncbi.nlm.nih.gov/pubmed/29155954
http://dx.doi.org/10.1093/nar/gkx1103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758917/
https://www.ncbi.nlm.nih.gov/pubmed/29155954
http://dx.doi.org/10.1093/nar/gkx1103

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