CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A

Pancreatic cancer is among the deadliest malignancies; however, the genetic events that lead to pancreatic carcinogenesis in adults remain unclear. In vivo models in which these genetic alterations occur in adult animals may more accurately reflect the features of human cancer. In this study, we dem...

Descripción completa

Detalles Bibliográficos
Autores principales: Tu, Q, Hao, J, Zhou, X, Yan, L, Dai, H, Sun, B, Yang, D, An, S, Lv, L, Jiao, B, Chen, C, Lai, R, Shi, P, Zhao, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759028/
https://www.ncbi.nlm.nih.gov/pubmed/28892048
http://dx.doi.org/10.1038/onc.2017.316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759028/
https://www.ncbi.nlm.nih.gov/pubmed/28892048
http://dx.doi.org/10.1038/onc.2017.316

Ejemplares similares