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A Short Route to the Ester (±) HomoSarkomycin via Johnson-Claisen Rearrangement

BACKGROUND: α-Methylene cycloalkanones are considered of interest because of their biological activity. Herein, in this paper the synthesis of (±) HomoSarkomycine Esters was described and characterized. METHODS: Using Bylis-Hillman adducts, triethlorthoacetate and propanoic acid, (±) HomoSarkomycine...

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Detalles Bibliográficos
Autores principales: Saied, M, Gatri, Rafik, Al-Ayed, Abdullah Sulaiman, Arfaoui, Youssef, El Gaied, Mohamed Moncef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759048/
https://www.ncbi.nlm.nih.gov/pubmed/29399007
http://dx.doi.org/10.2174/1570178614666161230123513