A-to-I RNA editing in the rat brain is age-dependent, region-specific and sensitive to environmental stress across generations

BACKGROUND: Adenosine-to-inosine (A-to-I) RNA editing is an epigenetic modification catalyzed by adenosine deaminases acting on RNA (ADARs), and is especially prevalent in the brain. We used the highly accurate microfluidics-based multiplex PCR sequencing (mmPCR-seq) technique to assess the effects...

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Detalles Bibliográficos
Autores principales: Zaidan, Hiba, Ramaswami, Gokul, Golumbic, Yaela N., Sher, Noa, Malik, Assaf, Barak, Michal, Galiani, Dalia, Dekel, Nava, Li, Jin B., Gaisler-Salomon, Inna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759210/
https://www.ncbi.nlm.nih.gov/pubmed/29310578
http://dx.doi.org/10.1186/s12864-017-4409-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759210/
https://www.ncbi.nlm.nih.gov/pubmed/29310578
http://dx.doi.org/10.1186/s12864-017-4409-8

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