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Utility of the Phenacyl Protecting Group in Traceless Protein Semisynthesis through Ligation–Desulfurization Chemistry
Semisynthesis of proteins via expressed protein ligation is a widely applicable method, even more so because of the possibility of ligation at non‐cysteine sites using β‐mercapto amino acids that can be converted to the corresponding native amino acids by desulfurization. A drawback of this ligation...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759462/ https://www.ncbi.nlm.nih.gov/pubmed/29321951 http://dx.doi.org/10.1002/open.201700180 |