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A Pilot Dose‐Finding Study of Etanercept in Rheumatoid Arthritis

A randomized, parallel‐dose study assessed the pharmacokinetics (PK) and pharmacodynamics (PD) of etanercept in 61 patients with rheumatoid arthritis (RA) who received doses from 10 mg once‐weekly to 50 mg twice‐weekly for 4 weeks. Empiric application of a maximal‐effect (E(max)) model to pooled ste...

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Detalles Bibliográficos
Autores principales: Breedveld, Ferdinand C., Jones, Heather E., Peifer, Kim, Korth‐Bradley, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759732/
https://www.ncbi.nlm.nih.gov/pubmed/28892591
http://dx.doi.org/10.1111/cts.12502