Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway

BACKGROUND: Breast cancer is one of the most commonly diagnosed invasive cancers among women around the world. Among several subtypes, triple negative breast cancer (TNBC) is highly aggressive and chemoresistant. Treatment of TNBC patients has been challenging due to heterogeneity and devoid of well...

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Detalles Bibliográficos
Autores principales: Kumar, Dhiraj, Haldar, Saikat, Gorain, Mahadeo, Kumar, Santosh, Mulani, Fayaj A., Yadav, Amit S., Miele, Lucio, Thulasiram, Hirekodathakallu V., Kundu, Gopal C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759831/
https://www.ncbi.nlm.nih.gov/pubmed/29310608
http://dx.doi.org/10.1186/s12885-017-3876-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759831/
https://www.ncbi.nlm.nih.gov/pubmed/29310608
http://dx.doi.org/10.1186/s12885-017-3876-2

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