WWL70 protects against chronic constriction injury-induced neuropathic pain in mice by cannabinoid receptor-independent mechanisms

BACKGROUND: Targeting the endocannabinoid system has emerged as an effective strategy for the treatment of inflammatory and neurological diseases. Unlike the inhibition of the principal 2-arachidonyl glycerol (2-AG) hydrolytic enzyme monoacylglycerol lipase (MAGL), which leads to 2-AG overload and c...

Descripción completa

Detalles Bibliográficos
Autores principales: Wen, Jie, Jones, Melissa, Tanaka, Mikiei, Selvaraj, Prabhuanand, Symes, Aviva J., Cox, Brian, Zhang, Yumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759843/
https://www.ncbi.nlm.nih.gov/pubmed/29310667
http://dx.doi.org/10.1186/s12974-017-1045-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759843/
https://www.ncbi.nlm.nih.gov/pubmed/29310667
http://dx.doi.org/10.1186/s12974-017-1045-9

Ejemplares similares