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The rs4846049 polymorphism in the 3′UTR region of the MTHFR gene increases the migraine susceptibility in an Iranian population

INTRODUCTION: Migraine is a painful complex neurovascular disease characterized by recurrent moderate-to-severe headaches. Increased level of homocysteine is related to dilation of cerebral vessels and endothelial injury that could trigger migraine attacks. Functional polymorphisms in the MTHFR gene...

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Detalles Bibliográficos
Autores principales: Salehi, Mohaddeseh, Amin-Beidokhti, Mona, Safarpour Lima, Behnam, Gholami, Milad, Javadi, Gholam-Reza, Mirfakhraie, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759854/
https://www.ncbi.nlm.nih.gov/pubmed/29379315
http://dx.doi.org/10.2147/JPR.S152930