Progranulin plasma levels predict the presence of GRN mutations in asymptomatic subjects and do not correlate with brain atrophy: results from the GENFI study

We investigated whether progranulin plasma levels are predictors of the presence of progranulin gene (GRN) null mutations or of the development of symptoms in asymptomatic at risk members participating in the Genetic Frontotemporal Dementia Initiative, including 19 patients, 64 asymptomatic carriers...

Descripción completa

Detalles Bibliográficos
Autores principales: Galimberti, Daniela, Fumagalli, Giorgio G., Fenoglio, Chiara, Cioffi, Sara M.G., Arighi, Andrea, Serpente, Maria, Borroni, Barbara, Padovani, Alessandro, Tagliavini, Fabrizio, Masellis, Mario, Tartaglia, Maria Carmela, van Swieten, John, Meeter, Lieke, Graff, Caroline, de Mendonça, Alexandre, Bocchetta, Martina, Rohrer, Jonathan D., Scarpini, Elio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759894/
https://www.ncbi.nlm.nih.gov/pubmed/29146050
http://dx.doi.org/10.1016/j.neurobiolaging.2017.10.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759894/
https://www.ncbi.nlm.nih.gov/pubmed/29146050
http://dx.doi.org/10.1016/j.neurobiolaging.2017.10.016

Ejemplares similares