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Investigation of quercetin and hyperoside as senolytics in adult human endothelial cells

Quercetin has been reported to act as a senolytic by selectively removing senescent endothelial cells, and thus it would seem quercetin could revolutionize the field of gerontology. However, given quercetin's narrow therapeutic index reported in work done with human umbilical vein endothelial c...

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Detalles Bibliográficos
Autores principales: Hwang, HyunTae V., Tran, Darlene Thuy, Rebuffatti, Michelle Nicole, Li, Chin-Shang, Knowlton, Anne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760026/
https://www.ncbi.nlm.nih.gov/pubmed/29315311
http://dx.doi.org/10.1371/journal.pone.0190374