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High-resolution global peptide-protein docking using fragments-based PIPER-FlexPepDock

Peptide-protein interactions contribute a significant fraction of the protein-protein interactome. Accurate modeling of these interactions is challenging due to the vast conformational space associated with interactions of highly flexible peptides with large receptor surfaces. To address this challe...

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Detalles Bibliográficos
Autores principales: Alam, Nawsad, Goldstein, Oriel, Xia, Bing, Porter, Kathryn A., Kozakov, Dima, Schueler-Furman, Ora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760072/
https://www.ncbi.nlm.nih.gov/pubmed/29281622
http://dx.doi.org/10.1371/journal.pcbi.1005905