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High-resolution global peptide-protein docking using fragments-based PIPER-FlexPepDock
Peptide-protein interactions contribute a significant fraction of the protein-protein interactome. Accurate modeling of these interactions is challenging due to the vast conformational space associated with interactions of highly flexible peptides with large receptor surfaces. To address this challe...
Autores principales: | Alam, Nawsad, Goldstein, Oriel, Xia, Bing, Porter, Kathryn A., Kozakov, Dima, Schueler-Furman, Ora |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760072/ https://www.ncbi.nlm.nih.gov/pubmed/29281622 http://dx.doi.org/10.1371/journal.pcbi.1005905 |
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