Loss-of-function of the ciliopathy protein Cc2d2a disorganizes the vesicle fusion machinery at the periciliary membrane and indirectly affects Rab8-trafficking in zebrafish photoreceptors

Ciliopathies are human disorders caused by dysfunction of primary cilia, ubiquitous organelles involved in transduction of environmental signals such as light sensation in photoreceptors. Concentration of signal detection proteins such as opsins in the ciliary membrane is achieved by RabGTPase-regul...

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Detalles Bibliográficos
Autores principales: Ojeda Naharros, Irene, Gesemann, Matthias, Mateos, José M., Barmettler, Gery, Forbes, Austin, Ziegler, Urs, Neuhauss, Stephan C. F., Bachmann-Gagescu, Ruxandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760100/
https://www.ncbi.nlm.nih.gov/pubmed/29281629
http://dx.doi.org/10.1371/journal.pgen.1007150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760100/
https://www.ncbi.nlm.nih.gov/pubmed/29281629
http://dx.doi.org/10.1371/journal.pgen.1007150

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