Association of papillomavirus E6 proteins with either MAML1 or E6AP clusters E6 proteins by structure, function, and evolutionary relatedness

Papillomavirus E6 proteins bind to LXXLL peptide motifs displayed on targeted cellular proteins. Alpha genus HPV E6 proteins associate with the cellular ubiquitin ligase E6AP (UBE3A), by binding to an LXXLL peptide (ELTLQELLGEE) displayed by E6AP, thereby stimulating E6AP ubiquitin ligase activity....

Descripción completa

Detalles Bibliográficos
Autores principales: Brimer, Nicole, Drews, Camille M., Vande Pol, Scott B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760104/
https://www.ncbi.nlm.nih.gov/pubmed/29281732
http://dx.doi.org/10.1371/journal.ppat.1006781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760104/
https://www.ncbi.nlm.nih.gov/pubmed/29281732
http://dx.doi.org/10.1371/journal.ppat.1006781

Ejemplares similares