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To what extent do structural changes in catalytic metal sites affect enzyme function?
About half of known enzymatic reactions involve metals. Enzymes belonging to the same superfamily often evolve to catalyze different reactions on the same structural scaffold. The work presented here investigates how functional differentiation, within superfamilies that contain metalloenzymes, relat...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760197/ https://www.ncbi.nlm.nih.gov/pubmed/29161638 http://dx.doi.org/10.1016/j.jinorgbio.2017.11.002 |