Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca(2+) Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU

Mitochondrial Ca(2+) uptake through the Ca(2+) uniporter supports cell functions, including oxidative metabolism, while meeting tissue-specific calcium signaling patterns and energy needs. The molecular mechanisms underlying tissue-specific control of the uniporter are unknown. Here, we investigated...

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Detalles Bibliográficos
Autores principales: Paillard, Melanie, Csordás, György, Szanda, Gergö, Golenár, Tünde, Debattisti, Valentina, Bartok, Adam, Wang, Nadan, Moffat, Cynthia, Seifert, Erin L., Spät, András, Hajnóczky, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760244/
https://www.ncbi.nlm.nih.gov/pubmed/28273446
http://dx.doi.org/10.1016/j.celrep.2017.02.032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760244/
https://www.ncbi.nlm.nih.gov/pubmed/28273446
http://dx.doi.org/10.1016/j.celrep.2017.02.032

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