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PREVALENCE OF GERMLINE MUTATIONS IN CANCER GENES AMONG PANCREATIC CANCER PATIENTS WITH POSITIVE FAMILY HISTORY

BACKGROUND: Panel-based genetic testing has identified increasing numbers of patients with pancreatic ductal adenocarcinoma (PDAC) who carry germline mutations. However, small sample sizes or number of genes evaluated limit prevalence estimates of these mutations. We estimated prevalence of mutation...

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Detalles Bibliográficos
Autores principales: Chaffee, Kari G., Oberg, Ann L., McWilliams, Robert R., Majithia, Neil, Allen, Brian A., Kidd, John, Singh, Nanda, Hartman, Anne-Renee, Wenstrup, Richard J., Petersen, Gloria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760284/
https://www.ncbi.nlm.nih.gov/pubmed/28726808
http://dx.doi.org/10.1038/gim.2017.85