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miR449a/SIRT1/PGC-1α Is Necessary for Mitochondrial Biogenesis Induced by T-2 Toxin

T-2 toxin is one of the type A trichothecenes produced mainly by the Fusarium genus. Due to its broad distribution and highly toxic nature, it is of great concern as a threat to human health and animal breeding. In addition to its ribotoxic effects, T-2 toxin exposure leads to mitochondrial dysfunct...

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Detalles Bibliográficos
Autores principales: Ma, Shijie, Zhao, Yurong, Sun, Jianwei, Mu, Peiqiang, Deng, Yiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760504/
https://www.ncbi.nlm.nih.gov/pubmed/29354057
http://dx.doi.org/10.3389/fphar.2017.00954