Neurofibromin 1 Impairs Natural Killer T-Cell-Dependent Antitumor Immunity against a T-Cell Lymphoma

Neurofibromin 1 (NF1) is a tumor suppressor gene encoding a Ras GTPase that negatively regulates Ras signaling pathways. Mutations in NF1 are linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. In terms of antitumor immunity, CD1d-dependent natural killer T (NKT...

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Detalles Bibliográficos
Autores principales: Liu, Jianyun, Gallo, Richard M., Khan, Masood A., Renukaradhya, Gourapura J., Brutkiewicz, Randy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760513/
https://www.ncbi.nlm.nih.gov/pubmed/29354122
http://dx.doi.org/10.3389/fimmu.2017.01901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760513/
https://www.ncbi.nlm.nih.gov/pubmed/29354122
http://dx.doi.org/10.3389/fimmu.2017.01901

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