Action Potential Recording and Pro-arrhythmia Risk Analysis in Human Ventricular Trabeculae

To assess drug-induced pro-arrhythmic risk, especially Torsades de Pointe (TdP), new models have been proposed, such as in-silico modeling of ventricular action potential (AP) and stem cell-derived cardiomyocytes (SC-CMs). Previously we evaluated the electrophysiological profile of 15 reference drug...

Descripción completa

Detalles Bibliográficos
Autores principales: Qu, Yusheng, Page, Guy, Abi-Gerges, Najah, Miller, Paul E., Ghetti, Andre, Vargas, Hugo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760531/
https://www.ncbi.nlm.nih.gov/pubmed/29354071
http://dx.doi.org/10.3389/fphys.2017.01109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760531/
https://www.ncbi.nlm.nih.gov/pubmed/29354071
http://dx.doi.org/10.3389/fphys.2017.01109

Ejemplares similares