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RFX1 and RFX3 Transcription Factors Interact with the D Sequence of Adeno-Associated Virus Inverted Terminal Repeat and Regulate AAV Transduction

Adeno-associated virus (AAV) transduction efficiency depends on the way in which cellular proteins process viral genomes in the nucleus. In this study, we have investigated the binding of nuclear proteins to the double stranded D (dsD) sequence of the AAV inverted terminal repeat (ITRs) by electromo...

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Detalles Bibliográficos
Autores principales: Julien, Laura, Chassagne, Julie, Peccate, Cécile, Lorain, Stéphanie, Piétri-Rouxel, France, Danos, Olivier, Benkhelifa-Ziyyat, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760533/
https://www.ncbi.nlm.nih.gov/pubmed/29317724
http://dx.doi.org/10.1038/s41598-017-18604-3