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Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells

CPT-11 is a first-line chemotherapeutic agent for the treatment of colorectal cancer in clinic. Previous studies including ours have demonstrated that CPT-11 is, however, toxic to the intestinal epithelium and resident peritoneal macrophages. By interacting with B1 cells, the resident peritoneal mac...

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Detalles Bibliográficos
Autores principales: Bai, Wen-Jing, Li, Chen-Guang, Zhang, Cheng-Cheng, Xu, Li-Hui, Zeng, Qiong-Zhen, Hu, Bo, Hong, Zhou, He, Xian-Hui, Ouyang, Dong-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760539/
https://www.ncbi.nlm.nih.gov/pubmed/29354128
http://dx.doi.org/10.3389/fimmu.2017.01919