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Deficiency of Carbonic Anhydrase II Results in a Urinary Concentrating Defect

Carbonic anhydrase II (CAII) is expressed along the nephron where it interacts with a number of transport proteins augmenting their activity. Aquaporin-1 (AQP1) interacts with CAII to increase water flux through the water channel. Both CAII and aquaporin-1 are expressed in the thin descending limb (...

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Detalles Bibliográficos
Autores principales: Krishnan, Devishree, Pan, Wanling, Beggs, Megan R., Trepiccione, Francesco, Chambrey, Régine, Eladari, Dominique, Cordat, Emmanuelle, Dimke, Henrik, Alexander, R. Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760551/
https://www.ncbi.nlm.nih.gov/pubmed/29354070
http://dx.doi.org/10.3389/fphys.2017.01108