ASPP2 Inhibits the Profibrotic Effects of Transforming Growth Factor-β1 in Hepatic Stellate Cells by Reducing Autophagy

BACKGROUND: Apoptosis-stimulating protein of p53-2 (ASPP2) is a damage-inducible P53-binding protein that enhances damage-induced apoptosis. Fibrosis is a wound-healing response, and hepatic stellate cells (HSCs) are key players in liver fibrogenesis. However, little is known about the relationship...

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Detalles Bibliográficos
Autores principales: Lin, Minghua, Chang, Yuan, Xie, Fang, Shi, Ying, Pang, Lijun, Chen, Dexi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760593/
https://www.ncbi.nlm.nih.gov/pubmed/29196956
http://dx.doi.org/10.1007/s10620-017-4816-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760593/
https://www.ncbi.nlm.nih.gov/pubmed/29196956
http://dx.doi.org/10.1007/s10620-017-4816-3

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