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Human cytomegalovirus-encoded US9 targets MAVS and STING signaling to evade type I interferon immune responses

Human cytomegalovirus (HCMV) has evolved sophisticated immune evasion mechanisms that target both the innate and adaptive immune responses. However, how HCMV encoded proteins are involved in this immune escape is not clear. Here, we show that HCMV glycoprotein US9 inhibits the IFN-β response by targ...

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Detalles Bibliográficos
Autores principales: Choi, Hyun jin, Park, Areum, Kang, Sujin, Lee, Eunhye, Lee, Taeyun A., Ra, Eun A., Lee, Jiseon, Lee, Sungwook, Park, Boyoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760629/
https://www.ncbi.nlm.nih.gov/pubmed/29317664
http://dx.doi.org/10.1038/s41467-017-02624-8