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Combined SEP and anti-PD-L1 antibody produces a synergistic antitumor effect in B16-F10 melanoma-bearing mice

The increased PD-L1 induces poorer prognosis in melanoma. The treatment with PD-1/PD-L1 antibodies have a low response rate. The combination immunotherapies are the encouraging drug development strategy to receive maximal therapeutic benefit. In this study, we investigated the enhanced antitumor and...

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Detalles Bibliográficos
Autores principales: Hu, Zhengping, Ye, Liang, Xing, Yingying, Hu, Jinhang, Xi, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760644/
https://www.ncbi.nlm.nih.gov/pubmed/29317734
http://dx.doi.org/10.1038/s41598-017-18641-y