Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis

Non-heme iron and α-ketoglutarate (αKG) oxygenases catalyze remarkably diverse reactions using a single ferrous ion cofactor. A major challenge in studying this versatile family of enzymes is to understand their structure–function relationship. AusE from Aspergillus nidulans and PrhA from Penicilliu...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakashima, Yu, Mori, Takahiro, Nakamura, Hitomi, Awakawa, Takayoshi, Hoshino, Shotaro, Senda, Miki, Senda, Toshiya, Abe, Ikuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760668/
https://www.ncbi.nlm.nih.gov/pubmed/29317628
http://dx.doi.org/10.1038/s41467-017-02371-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760668/
https://www.ncbi.nlm.nih.gov/pubmed/29317628
http://dx.doi.org/10.1038/s41467-017-02371-w

Ejemplares similares