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Alterations in the properties of the cell membrane due to glycosphingolipid accumulation in a model of Gaucher disease

Gaucher disease is a lysosomal storage disease characterized by the malfunction of glucocerebrosidase resulting in the accumulation of glucosylceramide and other sphingolipids in certain cells. Although the disease symptoms are usually attributed to the storage of undigested substrate in lysosomes,...

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Detalles Bibliográficos
Autores principales: Batta, Gyula, Soltész, Lilla, Kovács, Tamás, Bozó, Tamás, Mészár, Zoltán, Kellermayer, Miklós, Szöllősi, János, Nagy, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760709/
https://www.ncbi.nlm.nih.gov/pubmed/29317695
http://dx.doi.org/10.1038/s41598-017-18405-8