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Alterations in the properties of the cell membrane due to glycosphingolipid accumulation in a model of Gaucher disease
Gaucher disease is a lysosomal storage disease characterized by the malfunction of glucocerebrosidase resulting in the accumulation of glucosylceramide and other sphingolipids in certain cells. Although the disease symptoms are usually attributed to the storage of undigested substrate in lysosomes,...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760709/ https://www.ncbi.nlm.nih.gov/pubmed/29317695 http://dx.doi.org/10.1038/s41598-017-18405-8 |