Cargando…
The evolution of substrate discrimination in macrolide antibiotic resistance enzymes
The production of antibiotics by microbes in the environment and their use in medicine and agriculture select for existing and emerging resistance. To address this inevitability, prudent development of antibiotic drugs requires careful consideration of resistance evolution. Here, we identify the mol...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760710/ https://www.ncbi.nlm.nih.gov/pubmed/29317655 http://dx.doi.org/10.1038/s41467-017-02680-0 |