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Enhanced nasal drug delivery efficiency by increasing mechanical loading using hypergravity

Nasal route drug administration for local and systemic delivery of many therapeutics has received attention because the nasal cavity is highly vascularized and provides a large surface area for drug absorption. However, nasal mucosa exhibits limited permeability to polar molecules. In this study, we...

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Detalles Bibliográficos
Autores principales: Kim, Dongjoo, Kim, Young Hyo, Kwon, Soonjo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760728/
https://www.ncbi.nlm.nih.gov/pubmed/29317727
http://dx.doi.org/10.1038/s41598-017-18561-x