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Enhanced nasal drug delivery efficiency by increasing mechanical loading using hypergravity
Nasal route drug administration for local and systemic delivery of many therapeutics has received attention because the nasal cavity is highly vascularized and provides a large surface area for drug absorption. However, nasal mucosa exhibits limited permeability to polar molecules. In this study, we...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760728/ https://www.ncbi.nlm.nih.gov/pubmed/29317727 http://dx.doi.org/10.1038/s41598-017-18561-x |