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Identification of Head and Neck Cancer Subtypes Based on Human Papillomavirus Presence and E2F-Regulated Gene Expression

Human papillomavirus (HPV) is present in a subset of head and neck squamous cell carcinomas (HNSCCs). The cell cycle regulatory Rb-E2F pathway is a major target of HPV and is perturbed by these viruses in cell culture and animal models, as well as in human tumors. In this study, we examined differen...

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Detalles Bibliográficos
Autores principales: Johnson, Molly E., Cantalupo, Paul G., Pipas, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760753/
https://www.ncbi.nlm.nih.gov/pubmed/29359188
http://dx.doi.org/10.1128/mSphere.00580-17