Bio-analytical method development and validation of Rasagiline by high performance liquid chromatography tandem mass spectrometry detection and its application to pharmacokinetic study

The most suitable bio-analytical method based on liquid–liquid extraction has been developed and validated for quantification of Rasagiline in human plasma. Rasagiline-(13)C(3) mesylate was used as an internal standard for Rasagiline. Zorbax Eclipse Plus C18 (2.1 mm×50 mm, 3.5 μm) column provided ch...

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Detalles Bibliográficos
Autores principales: Konda, Ravi Kumar, Chandu, Babu Rao, Challa, B.R., Kothapalli, Chandrasekhar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760758/
https://www.ncbi.nlm.nih.gov/pubmed/29403764
http://dx.doi.org/10.1016/j.jpha.2012.04.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760758/
https://www.ncbi.nlm.nih.gov/pubmed/29403764
http://dx.doi.org/10.1016/j.jpha.2012.04.001

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