Determination of metabolite of nicergoline in human plasma by high-performance liquid chromatography and its application in pharmacokinetic studies

A fast, simple and sensitive high performance liquid chromatographic (HPLC) method has been developed for determination of 10α-methoxy-6-methyl ergoline-8β-methanol (MDL, a main metabolite of nicergoline) in human plasma. One-step liquid–liquid extraction (LLE) with diethyl ether was employed as the...

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Detalles Bibliográficos
Autores principales: Zheng, Rong, Wu, Yi-Hong, Jiang, De-Xi, Zhang, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760819/
https://www.ncbi.nlm.nih.gov/pubmed/29403722
http://dx.doi.org/10.1016/j.jpha.2011.09.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760819/
https://www.ncbi.nlm.nih.gov/pubmed/29403722
http://dx.doi.org/10.1016/j.jpha.2011.09.005

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